Hydroxyurea for Patients with Essential Thrombocythemia and a High Risk of Thrombosis

Cortelazzo, Sergio; Finazzi, Guido; Ruggeri, Marco; Vestri, Oscar; Galli, Monica; Rodeghiero, Francesco; Barbui, Tiziano

doi:10.1056/nejm199504273321704

Public

Hydroxyurea for Patients with Essential Thrombocythemia and a High Risk of Thrombosis

Published in New England Journal of Medicine • Apr 27, 1995

Authors:

Sergio Cortelazzo

Guido Finazzi

Marco Ruggeri

Abstract

BACKGROUND: Abnormalities in the number and function of platelets may contribute to thromboembolic complications in patients with essential thrombocythemia. We assessed whether maintaining the platelet count below 600,000 per cubic millimeter with hydroxyurea reduces the incidence of thrombosis in p...

Subject

Essential thrombocythemia

Medicine

Thrombosis

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