Toward a Biochemical Understanding of Human Intervertebral Disc Degeneration and Herniation

D. Kang, James; Stefanović-Račić, Maja; A. McIntyre, L.; I. Georgescu, H.; H. Evans, Christopher

doi:10.1097/00007632-199705150-00003

Public

Toward a Biochemical Understanding of Human Intervertebral Disc Degeneration and Herniation

Published in Spine • May 1, 1997

Authors:

James D. Kang

Maja Stefanović-Račić

L. A. McIntyre

Abstract

STUDY DESIGN: Normal and herniated human intervertebral disc specimens were cultured to study the effects of interleukin-1 beta on the production of nitric oxide, interleukin-6, prostaglandin E2, and matrix metalloproteinases. The effects of endogenously produced nitric oxide on the synthesis of oth...

Subject

Nitric oxide

Medicine

Intervertebral disc

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