Clozapine-Induced Agranulocytosis -- Incidence and Risk Factors in the United States

Ma. J. Alvir, Jose; A. Lieberman, Jeffrey; Z. Safferman, Allan; L. Schwimmer, Jeffrey; A. Schaaf, John

doi:10.1056/nejm199307153290303

Public

Clozapine-Induced Agranulocytosis -- Incidence and Risk Factors in the United States

Published in New England Journal of Medicine • Jul 15, 1993

Authors:

Jose Ma. J. Alvir

Jeffrey A. Lieberman

Allan Z. Safferman

Abstract

BACKGROUND: Clozapine is an atypical antipsychotic agent that is more effective than standard neuroleptic drugs in the treatment of patients with refractory schizophrenia. Unlike classic neuroleptic agents, clozapine is not associated with the development of acute extrapyramidal symptoms or tardive ...

Subject

Medicine

Clozapine

Incidence (geometry)

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