Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man

P. Smith, Eric; Boyd, Jeff; R. Frank, Graeme; Takahashi, Hiroyuki; M. Cohen, Robert; Specker, Bonny; C. Williams, Timothy; B. Lubahn, Dennis; S. Korach, Kenneth

doi:10.1056/nejm199410203311604

Public

Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man

Published in New England Journal of Medicine • Oct 20, 1994

Authors:

Eric P. Smith

Jeff Boyd

Graeme R. Frank

Abstract

BACKGROUND AND METHODS: Mutations in the estrogen-receptor gene have been thought to be lethal. A 28-year-old man whose estrogen resistance was caused by a disruptive mutation in the estrogen-receptor gene underwent studies of pituitary-gonadal function and bone density and received transdermal estr...

Subject

Endocrinology

Internal medicine

Estrogen

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!