Phenobarbital Compared with Phenytoin for the Treatment of Neonatal Seizures

J. Painter, Michael; S. Scher, Mark; D. Stein, Aryeh; Armatti, Stacey; Wang, Zhiming; C. Gardiner, Joseph; Paneth, Nigel; Minnigh, Beth; Alvin, John

doi:10.1056/nejm199908123410704

Public

Phenobarbital Compared with Phenytoin for the Treatment of Neonatal Seizures

Published in New England Journal of Medicine • Aug 12, 1999

Authors:

Michael J. Painter

Mark S. Scher

Aryeh D. Stein

Abstract

BACKGROUND: Seizures occur in 1 to 2 percent of neonates admitted to an intensive care unit. The treatment is usually with either phenobarbital or phenytoin, but the efficacy of the two drugs has not been compared directly. METHODS: From 1990 to 1995, we studied 59 neonates with seizures that were c...

Subject

Phenobarbital

Phenytoin

Medicine

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