A Randomized Controlled Pilot Trial of Modified Whole Blood versus Component Therapy in Severely Injured Patients Requiring Large Volume Transfusions

A. Cotton, Bryan; M. Podbielski, Jeanette; A. Camp, Elizabeth; Welch, Timothy; del Junco, Deborah; Bai, Yu; Hobbs, Rhonda; Scroggins, Jamie; Hartwell, Beth; A. Kozar, Rosemary; E. Wade, Charles; B. Holcomb, John

doi:10.1097/sla.0b013e3182a4ffa0

Public

A Randomized Controlled Pilot Trial of Modified Whole Blood versus Component Therapy in Severely Injured Patients Requiring Large Volume Transfusions

Published in Annals of Surgery • Aug 24, 2013

Authors:

Bryan A. Cotton

Jeanette M. Podbielski

Elizabeth A. Camp

Abstract

In Brief Objectives: To determine whether resuscitation of severely injured patients with modified whole blood (mWB) resulted in fewer overall transfusions compared with component (COMP) therapy. Background: For decades, whole blood (WB) was the primary product for resuscitating patients in hemorrha...

Subject

Medicine

Randomized controlled trial

Blood product

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