Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Paul Aiello, Lloyd; L. Avery, Robert; G. Arrigg, Paul; A. Keyt, Bruce; Jampel, Henry; T. Shah, Sabera; R. Pasquale, Louis; Thieme, Hagen; Iwamoto, Mami; E. Park, John; Hung Nguyen, Van; M. Aiello, Lloyd; Ferrara, Napoleone; L. King, George

doi:10.1056/nejm199412013312203

Public

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Published in New England Journal of Medicine • Dec 1, 1994

Authors:

Lloyd Paul Aiello

Robert L. Avery

Paul G. Arrigg

Abstract

BACKGROUND: Retinal ischemia induces intraocular neovascularization, which often leads to glaucoma, vitreous hemorrhage, and retinal detachment, presumably by stimulating the release of angiogenic molecules. Vascular endothelial growth factor (VEGF) is an endothelial-cell-specific angiogenic factor ...

Subject

Diabetic retinopathy

Medicine

Vascular endothelial growth factor

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