LncRNA—UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p

Bian, Zehua; Jin, Liugen; Zhang, Jiwei; Yin, Yuan; Quan, Chao; Hu, Yaling; Feng, Yuyang; Liu, Heyong; Fei, Bojian; Mao, Yong; Zhou, Leyuan; Qi, Xiaowei; Huang, Shenlin; Dong, Hua; Xing, Chungen; Huang, Zhaohui

doi:10.1038/srep23892

Public

LncRNA—UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p

Published in Scientific Reports • Apr 5, 2016

Authors:

Zehua Bian

Liugen Jin

Jiwei Zhang

Abstract

Recent preliminary studies reported the in vitro tumor-promoting effects of long non-coding RNA urothelial carcinoma associated 1 (UCA1) in colorectal cancer (CRC). However, the in vivo functions and molecular mechanism of UCA1 in CRC remain unclear. Therefore, we investigated the detailed role and ...

Subject

Colorectal cancer

CREB1

Cancer research

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