Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease

H. Present, Daniel; Rutgeerts, Paul; Targan, Stephan; B. Hanauer, Stephen; Mayer, Lloyd; A. van Hogezand, R.; K. Podolsky, Daniel; E. Sands, Bruce; Braakman, Tanja; L. DeWoody, Kimberly; Schaible, T; J. H. van Deventer, Sander

doi:10.1056/nejm199905063401804

Public

Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease

Published in New England Journal of Medicine • May 6, 1999

Authors:

Daniel H. Present

Paul Rutgeerts

Stephan Targan

Abstract

BACKGROUND: Enterocutaneous fistulas are a serious complication of Crohn's disease and are difficult to treat. Infliximab, a chimeric monoclonal antibody to tumor necrosis factor alpha, has recently been developed as a treatment for Crohn's disease. We conducted a randomized, multicenter, double-bli...

Subject

Medicine

Infliximab

Kilogram

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