Single-dose infusion ketamine and non-ketamine<i>N</i>-methyl-<scp>d</scp>-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories

Kishimoto, Taishiro; Mohan Chawla, Jatinder; Hagi, Katsuhiko; A. Zarate, Carlos; M. Kane, John; Bauer, Michael; U. Correll, Christoph

doi:10.1017/s0033291716000064

Public

Single-dose infusion ketamine and non-ketamineN-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories

Published in Psychological Medicine • Feb 12, 2016

Authors:

Taishiro Kishimoto

Jatinder Mohan Chawla

Katsuhiko Hagi

Abstract

BACKGROUND: Ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists (NMDAR antagonists) recently demonstrated antidepressant efficacy for the treatment of refractory depression, but effect sizes, trajectories and possible class effects are unclear. METHOD: We searched PubMed/PsycINFO/Web...

Subject

Ketamine

Placebo

Discontinuation

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