The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure

Packer, Milton; R. Bristow, Michael; N. Cohn, Jay; S. Colucci, Wilson; B. Fowler, Michael; M. Gilbert, Edward; H. Shusterman, Neil

doi:10.1056/nejm199605233342101

Public

The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure

Published in New England Journal of Medicine • May 23, 1996

Authors:

Milton Packer

Michael R. Bristow

Jay N. Cohn

Abstract

BACKGROUND: Controlled clinical trials have shown that beta-blockers can produce hemodynamic and symptomatic improvement in chronic heart failure, but the effect of these drugs on survival has not been determined. METHODS: We enrolled 1094 patients with chronic heart failure in a double-blind, place...

Subject

Medicine

Carvedilol

Heart failure

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