Phenotype, development, and biological function of myeloid-derived suppressor cells

Zhao, Yang; Zhao, Yang; Wu, Tingting; Shao, Steven; Shi, Bingyi; Zhao, Yong; Zhao, Yong

doi:10.1080/2162402x.2015.1004983

Public

Phenotype, development, and biological function of myeloid-derived suppressor cells

Published in OncoImmunology • Oct 14, 2015

Authors:

Yang Zhao

Tingting Wu

Abstract

CD11b+Gr-1+ myeloid-derived suppressor cells (MDSCs) are an important population of innate regulatory cells mainly comprising monocytic MDSCs (M-MDSCs) with a phenotype of CD11b+Ly6G−Ly6Chigh and granulocytic MDSCs (G-MDSCs) with a phenotype of CD11b+Ly6G+Ly6Clow in mice. They play crucial roles in ...

Subject

Myeloid-derived Suppressor Cell

Immunology

Cancer research

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