Liposomal Amphotericin B for Empirical Therapy in Patients with Persistent Fever and Neutropenia

J. Walsh, Thomas; W. Finberg, Robert; Arndt, Carola; Hiemenz, John; L. Schwartz, Cindy; Bodensteiner, David; G. Pappas, Peter; L. Seibel, Nita; N. Greenberg, Richard; Dummer, Stephen; G. Schuster, Mindy; E. Dismukes, William; S. Holcenberg, John

doi:10.1056/nejm199903113401004

Public

Liposomal Amphotericin B for Empirical Therapy in Patients with Persistent Fever and Neutropenia

Published in New England Journal of Medicine • Mar 11, 1999

Authors:

Thomas J. Walsh

Robert W. Finberg

Carola Arndt

Abstract

BACKGROUND: In patients with persistent fever and neutropenia, amphotericin B is administered empirically for the early treatment and prevention of clinically occult invasive fungal infections. However, breakthrough fungal infections can develop despite treatment, and amphotericin B has substantial ...

Subject

Amphotericin B

Medicine

Neutropenia

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