Dynamics of Completely Unfolded and Native Proteins through Solid-State Nanopores as a Function of Electric Driving Force

Oukhaled, Abdelghani; Cressiot, Benjamin; Bacri, Laurent; Pastoriza‐Gallego, Manuela; Betton, Jean‐Michel; Le Bourhis, Éric; Jede, R.; Giérak, J.; Auvray, Loïc; Pelta, Juan

doi:10.1021/nn1034795

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Dynamics of Completely Unfolded and Native Proteins through Solid-State Nanopores as a Function of Electric Driving Force

Published in ACS Nano • Apr 8, 2011

Authors:

Abdelghani Oukhaled

Benjamin Cressiot

Laurent Bacri

Abstract

We report experimentally the dynamic properties of the entry and transport of unfolded and native proteins through a solid-state nanopore as a function of applied voltage, and we discuss the experimental data obtained as compared to theory. We show an exponential increase in the event frequency of c...

Subject

Nanopore

Chemical physics

Unfolded protein response

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