Prevention of Radiographic-Contrast-Agent–Induced Reductions in Renal Function by Acetylcysteine

Tepel, Martin; van der Giet, Markus; Schwarzfeld, Carola; Laufer, Ulf; Liermann, Dieter; Zidek, Walter

doi:10.1056/nejm200007203430304

Public

Prevention of Radiographic-Contrast-Agent–Induced Reductions in Renal Function by Acetylcysteine

Published in New England Journal of Medicine • Jul 20, 2000

Authors:

Martin Tepel

Markus van der Giet

Carola Schwarzfeld

Abstract

BACKGROUND: Radiographic contrast agents can cause a reduction in renal function that may be due to reactive oxygen species. Whether the reduction can be prevented by the administration of antioxidants is unknown. METHODS: We prospectively studied 83 patients with chronic renal insufficiency (mean [...

Subject

Medicine

Creatinine

Liter

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