Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest

J. Kudenchuk, Peter; P. Brown, Siobhan; Daya, Mohamud; D. Rea, Thomas; Nichol, Graham; J. Morrison, Laurie; G. Leroux, Brian; Vaillancourt, Christian; Wittwer, Lynn; W. Callaway, Clifton; Christenson, James; Egan, Debra; P. Ornato, Joseph; L. Weisfeldt, Myron; G. Stiell, Ian; H. Idris, Ahamed; P. Aufderheide, Tom; V. Dunford, James; Riccardo Colella, M.; M. Vilke, Gary; Brienza, Ashley; Desvigne‐Nickens, Patrice; C. Gray, Pamela; Gray, Randal; Seals, Norman; Straight, Ron; Dorian, Paul

doi:10.1056/nejmoa1514204

Public

Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest

Published in New England Journal of Medicine • Apr 4, 2016

Authors:

Peter J. Kudenchuk

Siobhan P. Brown

Mohamud Daya

Abstract

BACKGROUND: Antiarrhythmic drugs are used commonly in out-of-hospital cardiac arrest for shock-refractory ventricular fibrillation or pulseless ventricular tachycardia, but without proven survival benefit. METHODS: In this randomized, double-blind trial, we compared parenteral amiodarone, lidocaine,...

Subject

Medicine

Lidocaine

Amiodarone

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