Nitrovasodilators, Low-Dose Aspirin, Other Nonsteroidal Antiinflammatory Drugs, and the Risk of Upper Gastrointestinal Bleeding

Lanas, Ángel; Bajador, Eduardo; Serrano, Pedro; Fuentes, Javier; Carreño, Sofía; Llaó Guárdia, J.; Sanz, Mercedes; Montoro, Miguel; Lemos Sainz, Ricardo

doi:10.1056/nejm200009213431202

Public

Nitrovasodilators, Low-Dose Aspirin, Other Nonsteroidal Antiinflammatory Drugs, and the Risk of Upper Gastrointestinal Bleeding

Published in New England Journal of Medicine • Sep 21, 2000

Authors:

Ángel Lanas

Eduardo Bajador

Pedro Serrano

Abstract

UNLABELLED: BACKGROUND The relation between medications that release nitric oxide, such as nitroglycerin and other nitrovasodilators, and upper gastrointestinal bleeding is uncertain. In animals, these medications reduce the gastric damage induced by nonsteroidal antiinflammatory drugs. Nitric oxide...

Subject

Medicine

Aspirin

Odds ratio

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