Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

Omar Sangaré, Lamba; Dilezitoko Alayi, Tchilabalo; Westermann, Benoit; Hovasse, Agnes; Sindikubwabo, Fabien; Callebaut, Isabelle; Werkmeister, Elisabeth; Lafont, Frank; Slomianny, Christian; Hakimi, Mohamed-Ali; Van Dorsselaer, Alain; Schaeffer-Reiss, Christine; Tomavo, Stanislas

doi:10.1038/ncomms11191

Public

Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

Shared by NobleBlocks on Apr 11, 2016 • 12:00 AM UTC

Authors:

Lamba Omar Sangaré

Tchilabalo Dilezitoko Alayi

Benoit Westermann

Abstract

Abstract Membrane trafficking pathways play critical roles in Apicomplexa, a phylum of protozoan parasites that cause life-threatening diseases worldwide. Here we report the first retromer-trafficking interactome in Toxoplasma gondii. This retromer complex includes a trimer Vps35–Vps26–Vps29 core co...

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