Omeprazole Compared with Misoprostol for Ulcers Associated with Nonsteroidal Antiinflammatory Drugs

J. Hawkey, Christopher; A. Karrasch, Jeffrey; Szczepański, L; G. Walker, Donald; Barkun, Alan; J Swannell, A; D. Yeomans, Neville

doi:10.1056/nejm199803123381105

Public

Omeprazole Compared with Misoprostol for Ulcers Associated with Nonsteroidal Antiinflammatory Drugs

Published in New England Journal of Medicine • Mar 12, 1998

Authors:

Christopher J. Hawkey

Jeffrey A. Karrasch

L Szczepański

Abstract

BACKGROUND: Misoprostol is effective for ulcers associated with the use of nonsteroidal antiinflammatory drugs (NSAIDs) but is often poorly tolerated because of diarrhea and abdominal pain. We compared the efficacy of omeprazole and misoprostol in healing and preventing ulcers associated with NSAIDs...

Subject

Omeprazole

Medicine

Misoprostol

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