All-trans-Retinoic Acid in Acute Promyelocytic Leukemia

S. Tallman, Martin; W. Andersen, Janet; A. Schiffer, Charles; R. Appelbaum, Frederick; H. Feusner, James; Ogden, Angela; E. Shepherd, Lois; L. Willman, Cheryl; D. Bloomfield, Clara; M. Rowe, Jacob; H. Wiernik, Peter

doi:10.1056/nejm199710093371501

Public

All-trans-Retinoic Acid in Acute Promyelocytic Leukemia

Published in New England Journal of Medicine • Oct 9, 1997

Authors:

Martin S. Tallman

Janet W. Andersen

Charles A. Schiffer

Abstract

BACKGROUND: All-trans-retinoic acid induces complete remission in acute promyelocytic leukemia. However, it is not clear whether induction therapy with all-trans-retinoic acid is superior to chemotherapy alone or whether maintenance treatment with all-trans-retinoic acid improves outcome. METHODS: T...

Subject

Acute promyelocytic leukemia

Retinoic acid

Medicine

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