Postoperative Chemotherapy and Delayed Radiation in Children Less Than Three Years of Age with Malignant Brain Tumors

K. Duffner, Patricia; E. Horowitz, Marc; P. Krischer, Jeffrey; S. Friedman, Henry; C. Burger, Peter; E. Cohen, Michael; A. Sanford, Robert; K. Mulhern, Raymond; E. James, Hector; Freeman, Carolyn; Glen Seidel, F.; E. Kun, Larry

doi:10.1056/nejm199306173282401

Public

Postoperative Chemotherapy and Delayed Radiation in Children Less Than Three Years of Age with Malignant Brain Tumors

Published in New England Journal of Medicine • Jun 17, 1993

Authors:

Patricia K. Duffner

Marc E. Horowitz

Jeffrey P. Krischer

Abstract

BACKGROUND: Among patients with malignant brain tumors, infants and very young children have the worst prognosis and the most severe treatment-related neurotoxic effects. Therefore, in 1986, the Pediatric Oncology Group began a study in which postoperative chemotherapy was given in order to permit a...

Subject

Medicine

Chemotherapy

Radiation therapy

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