Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma

Négrier, Sylvie; Escudier, Bernard; Lasset, Christine; Douillard, Jean‐Yves; Savary, J.; Chevreau, Christine; Ravaud, Alain; Mercatello, A.; Pény, J; Mousseau, Mireille; Philip, Thierry; Tursz, Thomas

doi:10.1056/nejm199804303381805

Public

Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma

Published in New England Journal of Medicine • Apr 30, 1998

Authors:

Sylvie Négrier

Bernard Escudier

Christine Lasset

Abstract

BACKGROUND: Recombinant human interleukin-2 (aldesleukin) and recombinant human interferon alfa can induce notable tumor regression in a limited number of patients with metastatic renal-cell carcinoma. We conducted a multicenter, randomized trial to determine the effect of each cytokine independentl...

Subject

Medicine

Renal cell carcinoma

Interferon alfa

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