Implementation of Nationwide Real-time Whole-genome Sequencing to Enhance Listeriosis Outbreak Detection and Investigation

R. Jackson, Brendan; L. Tarr, Cheryl; Strain, Errol; A. Jackson, Kelly; Conrad, Amanda; A. Carleton, Heather; S. Katz, Lee; Stroika, Steven; Hannah Gould, L.; K. Mody, Rajal; J. Silk, Benjamin; Beal, Jennifer; Chen, Yi; Timme, Ruth; Doyle, Matthew; Fields, Angela; E. Wise, Matthew; E. Tillman, Glenn; Defibaugh-Chávez, Stephanie; Kučerová, Zuzana; Sabol, Ashley; Roache, Katie; Trees, Eija; Simmons, Mustafa; Wasilenko, Jamie; Kubota, Kristy; Pouseele, Hannes; Klimke, William; M. Besser, John; W. Brown, Eric; W. Allard, Marc; Gerner‐Smidt, Peter

doi:10.1093/cid/ciw242

Public

Implementation of Nationwide Real-time Whole-genome Sequencing to Enhance Listeriosis Outbreak Detection and Investigation

Published in Clinical Infectious Diseases • Apr 18, 2016

Authors:

Brendan R. Jackson

Cheryl L. Tarr

Errol Strain

Abstract

Listeria monocytogenes (Lm) causes severe foodborne illness (listeriosis). Previous molecular subtyping methods, such as pulsed-field gel electrophoresis (PFGE), were critical in detecting outbreaks that led to food safety improvements and declining incidence, but PFGE provides limited genetic resol...

Subject

Subtyping

Outbreak

Whole genome sequencing

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