Improvement in Glucose Tolerance and Insulin Resistance in Obese Subjects Treated with Troglitazone

J. Nolan, John; Ludvik, Bernhard; Beerdsen, P.; Joyce, M.; M. Olefsky, Jerrold

doi:10.1056/nejm199411033311803

Public

Improvement in Glucose Tolerance and Insulin Resistance in Obese Subjects Treated with Troglitazone

Published in New England Journal of Medicine • Nov 3, 1994

Authors:

John J. Nolan

Bernhard Ludvik

P. Beerdsen

Abstract

BACKGROUND: Troglitazone decreases insulin resistance and hyperglycemia in patients with non-insulin-dependent diabetes mellitus (NIDDM), but its effects on subjects without diabetes are not known. METHODS: We performed oral and intravenous glucose-tolerance tests, studies with the euglycemic-hyperi...

Subject

Troglitazone

Medicine

Insulin resistance

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