Elevated Serum IgG4 Levels in Diagnosis, Treatment Response, Organ Involvement, and Relapse in a Prospective IgG4-Related Disease UK Cohort

Culver, Emma; Sadler, Ross; B. Simpson, Dawn; Cargill, Tamsin; Makuch, Mateusz; C Bateman, Adrian; Ellis, Anthony; Collier, Jane; W. Chapman, Roger; Klenerman, Paul; Barnes, Eleanor; Ferry, Berne

doi:10.1038/ajg.2016.40

Public

Elevated Serum IgG4 Levels in Diagnosis, Treatment Response, Organ Involvement, and Relapse in a Prospective IgG4-Related Disease UK Cohort

Published in The American Journal of Gastroenterology • Apr 19, 2016

Authors:

Emma Culver

Ross Sadler

Dawn B. Simpson

Abstract

OBJECTIVES: Elevated serum immunoglobulin G4 (IgG4) levels have been associated with autoimmune pancreatitis and IgG4-related disease (IgG4-RD) for over a decade. However, an elevated serum IgG4 is not specific for the disease. There have been inconsistent reports of its use in diagnosis, as a marke...

Subject

Medicine

IgG4-related disease

Autoimmune pancreatitis

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