Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis

D. Gillmore, Julian; J. Maurer, Matthew; H. Falk, Rodney; Merlini, Giampaolo; Damy, Thibaud; Dispenzieri, Angela; Wechalekar, Ashutosh; L. Berk, John; Cristina Quarta, Candida; Grogan, Martha; J. Lachmann, Helen; Bokhari, Sabahat; Castaño, Adam; Dorbala, Sharmila; B. Johnson, Geoffrey; W.J.M. Glaudemans, Andor; Rezk, Tamer; Fontana, Marianna; Palladini, Giovanni; Milani, Paolo; Guidalotti, Pierluigi; Flatman, Katarina; Lane, Thirusha; W. Vonberg, Frederick; Whelan, Carol; Moon, James; L. Ruberg, Frederick; J. Miller, Edward; F. Hutt, David; P. C. Hazenberg, Bouke; Rapezzi, Claudio; N. Hawkins, Philip

doi:10.1161/circulationaha.116.021612

Public

Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis

Published in Circulation • Apr 23, 2016

Authors:

Julian D. Gillmore

Matthew J. Maurer

Rodney H. Falk

Abstract

BACKGROUND: Cardiac transthyretin (ATTR) amyloidosis is a progressive and fatal cardiomyopathy for which several promising therapies are in development. The diagnosis is frequently delayed or missed because of the limited specificity of echocardiography and the traditional requirement for histologic...

Subject

Medicine

Cardiac amyloidosis

Amyloidosis

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