A One-Year Trial of Lamivudine for Chronic Hepatitis B

Lai, Ching‐Lung; Chien, Rong‐Nan; W.Y. Leung, Nancy; Chang, Ting‐Tsung; Guan, Richard; Tai, Dar‐In; Ng, Keng–Yeen; Wu, Pui–Chee; C. Dent, Julie; Barber, Judy; L. Stephenson, Sally; Gray, DF

doi:10.1056/nejm199807093390201

Public

A One-Year Trial of Lamivudine for Chronic Hepatitis B

Published in New England Journal of Medicine • Jul 9, 1998

Authors:

Ching‐Lung Lai

Rong‐Nan Chien

Nancy W.Y. Leung

Abstract

BACKGROUND AND METHODS: In preliminary trials, lamivudine, an oral nucleoside analogue, has shown promise for the treatment of chronic hepatitis B. We conducted a one-year, double-blind trial of lamivudine in 358 Chinese patients with chronic hepatitis B. The patients were randomly assigned to recei...

Subject

Lamivudine

Medicine

Placebo

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