A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

M. Hammer, Scott; Squires, Kathleen; D. Hughes, Michael; M. Grimes, Janet; M. Demeter, Lisa; S. Currier, Judith; J. Eron, Joseph; Feinberg, Judith; H. Balfour, Henry; Deyton, Lawrence; Chodakewitz, Jeffrey; A. Fischl, Margaret; Phair, John; Pedneault, Louise; Nguyen, Bach‐Yen; C. Cook, Jon

doi:10.1056/nejm199709113371101

Public

A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

Published in New England Journal of Medicine • Sep 11, 1997

Authors:

Scott M. Hammer

Kathleen Squires

Michael D. Hughes

Abstract

BACKGROUND: The efficacy and safety of adding a protease inhibitor to two nucleoside analogues to treat human immunodeficiency virus type 1 (HIV-1) infection are not clear. We compared treatment with the protease inhibitor indinavir in addition to zidovudine and lamivudine with treatment with the tw...

Subject

Indinavir

Lamivudine

Zidovudine

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