A Randomized, Controlled Trial of Interferon Alfa-2b Alone and after Prednisone Withdrawal for the Treatment of Chronic Hepatitis B

P. Perrillo, Robert; R. Schiff, Eugene; L. Davis, Gary; C. Bodenheimer, Henry; L. Lindsay, Karen; A. Payne, John; L. Dienstag, Jules; O'Brien, Christopher; H. Tamburro, Carlo; M. Jacobson, Ira; E. Sampliner, Richard; Feit, David; H. Lefkowitch, Jay; C. Kuhns, Mary; Meschievitz, Carlton; Sanghvi, Bharati; K. Albrecht, Janice; L. Gibas, Alexandra

doi:10.1056/nejm199008023230503

Public

A Randomized, Controlled Trial of Interferon Alfa-2b Alone and after Prednisone Withdrawal for the Treatment of Chronic Hepatitis B

Published in New England Journal of Medicine • Aug 2, 1990

Authors:

Robert P. Perrillo

Eugene R. Schiff

Gary L. Davis

Abstract

BACKGROUND AND METHODS: Chronic hepatitis B is a common and often progressive liver disorder for which there is no accepted therapy. To assess the efficacy of treatment with interferon, we randomly assigned patients with chronic hepatitis B to one of the following regimens: prednisone for 6 weeks fo...

Subject

Medicine

Prednisone

Interferon alfa

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