A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation

L. Goodman, Jesse; J. Winston, Drew; A. Greenfield, Ronald; Chandrasekar, Pranatharthi; Fox, Barry; Kaizer, Herbert; K. Shadduck, Richard; C. Shea, Thomas; J. Stiff, Patrick; J. Friedman, David; G. Powderly, William; L. Silber, Jeffrey; W. Horowitz, Harold; Lichtin, Alan; N. Wolff, Steven; F. Mangan, Kenneth; Silver, Samuel; J. Weisdorf, Daniel; G. Ho, Winston; Gilbert, Gene; N. Buell, Donald

doi:10.1056/nejm199203263261301

Public

A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation

Published in New England Journal of Medicine • Mar 26, 1992

Authors:

Jesse L. Goodman

Drew J. Winston

Ronald A. Greenfield

Abstract

BACKGROUND AND METHODS: Superficial and systemic fungal infections are a major problem among severely immunocompromised patients who undergo bone marrow transplantation. We performed a double-blind, randomized, multicenter trial in which patients receiving bone marrow transplants were randomly assig...

Subject

Medicine

Fluconazole

Placebo

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