Oral versus Intravenous Empirical Antimicrobial Therapy for Fever in Patients with Granulocytopenia Who Are Receiving Cancer Chemotherapy

V. Kern, Winfried; Cometta, Alain; De Bock, R.; Langenaeken, John; Paesmans, Marianne; Zanetti, Giorgio; Calandra, Thierry; P. Glauser, M.; Crokaert, F.; Klášterský, Jean; Skoutelis, Athanasios; P. Bassaris, Harry; H. Zinner, Stephen; Viscoli, Claudio; Engelhard, Dan; Padmos, Andrew; Gaya, Harold

doi:10.1056/nejm199907293410502

Public

Oral versus Intravenous Empirical Antimicrobial Therapy for Fever in Patients with Granulocytopenia Who Are Receiving Cancer Chemotherapy

Published in New England Journal of Medicine • Jul 29, 1999

Authors:

Winfried V. Kern

Alain Cometta

R. De Bock

Abstract

BACKGROUND: Intravenously administered antimicrobial agents have been the standard choice for the empirical management of fever in patients with cancer and granulocytopenia. If orally administered empirical therapy is as effective as intravenous therapy, it would offer advantages such as improved qu...

Subject

Medicine

Regimen

Ceftriaxone

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