Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

H. Sohn, Elliott; W. van Dijk, Hille; Jiao, Chunhua; H. B. Kok, Pauline; Jeong, Woojin; Demirkaya, Nazli; Garmager, Allison; Wit, Ferdinand; Küçükevcilioğlu, Murat; E. J. van Velthoven, Mirjam; Hans DeVries, J.; F. Mullins, Robert; H. Kuehn, Markus; O. Schlingemann, Reinier; Sonka, Milan; D. Verbraak, Frank; D. Abràmoff, Michael

doi:10.1073/pnas.1522014113

Public

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

Published in Proceedings of the National Academy of Sciences • Apr 25, 2016

Authors:

Elliott H. Sohn

Hille W. van Dijk

Chunhua Jiao

Abstract

Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in people with diabetes mellitus (DM). We report that in 45 people with DM and no to minimal DR there was significant, progr...

Subject

Diabetic retinopathy

Retinal

Medicine

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