Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies

Ulbrich, Karel; Holá, Kateřina; Šubr, Vladimír; Bakandritsos, Aristides; Tuček, Jiří; Zbořil, Radek

doi:10.1021/acs.chemrev.5b00589

Public

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies

Published in Chemical Reviews • Apr 25, 2016

Authors:

Karel Ulbrich

Kateřina Holá

Vladimír Šubr

Abstract

Targeted delivery combined with controlled drug release has a pivotal role in the future of personalized medicine. This review covers the principles, advantages, and drawbacks of passive and active targeting based on various polymer and magnetic iron oxide nanoparticle carriers with drug attached by...

Subject

Chemistry

Covalent bond

Drug delivery

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