RAD51B in Familial Breast Cancer

M. Pelttari, Liisa; Khan, Sofia; Vuorela, Mikko; I. Kiiski, Johanna; Vilske, Sara; Nevanlinna, Viivi; Ranta, Salla; Schleutker, Johanna; Winqvist, Robert; Kallioniemi, Anne; Dörk, Thilo; Bogdanova, Natalia; D. Figueroa, Jonine; D.P. Pharoah, Paul; K. Schmidt, Marjanka; M. Dunning, Alison; García‐Closas, Montserrat; K. Bolla, Manjeet; Dennis, Joe; Michailidou, Kyriaki; Wang, Qin; L. Hopper, John; C. Southey, Melissa; H. Rosenberg, Efraim; A. Fasching, Peter; W. Beckmann, Matthias; Peto, Julian; dos‐Santos‐Silva, Isabel; J. Sawyer, Elinor; Tomlinson, Ian; Burwinkel, Barbara; Surowy, Harald; Guénel, Pascal; Truong, Thérèse; E. Bojesen, Stig; G. Nordestgaard, Børge; Benı́tez, Javier; González‐Neira, Anna; L. Neuhausen, Susan; Anton‐Culver, Hoda; Brenner, Hermann; Arndt, Volker; Meindl, Alfons; K. Schmutzler, Rita; Brauch, Hiltrud; Brüning, Thomas; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; M. Hartikainen, Jaana; Chenevix‐Trench, Georgia; Investigators, kConFab/AOCS; Van Dyck, Laurien; Janssen, Hilde; Chang-Claude, Jenny; Rudolph, Anja; Radice, Paolo; Peterlongo, Paolo; Hallberg, Emily; E. Olson, Janet; G. Giles, Graham; L. Milne, Roger; A. Haiman, Christopher; R. Schumacher, Fredrick; Simard, Jacques; Dumont, Martine; Kristensen, Vessela; Børresen‐Dale, Anne‐Lise; Zheng, Wei; Beeghly‐Fadiel, Alicia; Grip, Mervi; L. Andrulis, Irene; Glendon, Gord; Devilee, Peter; Seynaeve, Caroline; J. Hooning, Maartje; Collée, Margriet; Cox, Angela; S. Cross, Simon; Shah, Mitul; Luben, Robert; Hamann, Ute; Torres, Diana; Jakubowska, Anna; Lubiński, Jan; J. Couch, Fergus; Yannoukakos, Drakoulis; Orr, Nick; J. Swerdlow, Anthony; Darabi, Hatef; Li, Jingmei; Czene, Kamila; Hall, Per; F. Easton, Douglas; Mattson, Johanna; Blomqvist, Carl; Aittomäki, Kristiina; Nevanlinna, Heli

doi:10.1371/journal.pone.0153788

Public

RAD51B in Familial Breast Cancer

Published in PLoS ONE • May 5, 2016

Authors:

Liisa M. Pelttari

Sofia Khan

Mikko Vuorela

Abstract

Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, ...

Subject

Breast cancer

Odds ratio

Single-nucleotide polymorphism

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