Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, Aysu; Beauchamp, Jonathan; Alan Fontana, Mark; J. Lee, James; H. Pers, Tune; A. Rietveld, Cornelius; Turley, Patrick; Chen, Guo‐Bo; Emilsson, Valur; Fleur W. Meddens, S.; Oskarsson, Sven; K. Pickrell, Joseph; Thom, Kevin; Timshel, Pascal; de Vlaming, Ronald; Abdellaoui, Abdel; S. Ahluwalia, Tarunveer; Bačelis, Jonas; Baumbach, Clemens; Björnsdóttir, Gyða; Brandsma, J; Pina Concas, Maria; Derringer, Jaime; A. Furlotte, Nicholas; E. Galesloot, Tessel; Girotto, Giorgia; Gupta, Richa; M. Hall, Leanne; E. Harris, Sarah; Hofer, Edith; Horikoshi, Momoko; E. Huffman, Jennifer; Kaasik, Kadri; Panagiota Kalafati, Ioanna; Karlsson, Robert; Kong, Augustine; Lahti, Jari; J. van der Lee, Sven; deLeeuw, C.; A. Lind, Penelope; Lindgren, Karl‐Oskar; Liu, Tian; Mangino, Massimo; Marten, Jonathan; Mihailov, Evelin; B. Miller, Michael; J. van der Most, Peter; Oldmeadow, Christopher; Payton, Antony; Pervjakova, Natalia; J. Peyrot, Wouter; Qian, Yong; Raitakari, Olli; Rueedi, Rico; Salvi, Erika; Schmidt, Börge; E. Schraut, Katharina; Shi, Jianxin; V. Smith, Albert; A. Poot, Raymond; St Pourcain, Beaté; Teumer, Alexander; Thorleifsson, Gudmar; Verweij, Niek; Vuckovic, Dragana; Wellmann, Juergen; Westra, Harm-Jan; Yang, Jingyun; Zhao, Wei; Zhu, Zhihong; Z. Alizadeh, Behrooz; Amin, Najaf; Bakshi, Andrew; E. Baumeister, Sebastian; Biino, Ginevra; Bønnelykke, Klaus; A. Boyle, Patricia; Campbell, Harry; P. Cappuccio, Francesco; Davies, Gail; De Neve, Jan-Emmanuel; Deloukas, Panos; Demuth, Ilja; Ding, Jun; Eibich, Peter; Eisele, Lewin; Eklund, Niina; M. Evans, David; D. Faul, Jessica; F. Feitosa, Mary; J. Forstner, Andreas; Gandin, Ilaria; Gunnarsson, Bjarni; V. Halldórsson, Bjarni; B. Harris, Tamara; C. Heath, Andrew; J. Hocking, Lynne; G. Holliday, Elizabeth; Homuth, Georg; A. Horan, Michael; Hottenga, Jouke-Jan; L De Jager, Philip; K. Joshi, Peter; Jugessur, Astanand; A. Kaakinen, Marika; Kähönen, Mika; Kanoni, Stavroula; Keltigangas-Järvinen, Liisa; A. Kiemeney, Lambertus; Kolčić, Ivana; Koskinen, Seppo; T. Kraja, Aldi; Kroh, Martin; Kutalik, Zoltán; Latvala, Antti; J. Launer, L.; P. Lebreton, Maël; F. Levinson, Douglas; Lichtenstein, Paul; Lichtner, Peter; C. Liewald, David; Cohort Study, Lifelines; Loukola, Anu; A. Madden, Pamela; Mägi, Reedik; Mäki‐Opas, Tomi; E. Marioni, Riccardo; Marques‐Vidal, Pedro; A. Meddens, Gerardus; McMahon, George; Meisinger, Christa; Meitinger, Thomas; Milaneschi, Yusplitri; Milani, Lili; W. Montgomery, Grant; Myhre, Ronny; P. Nelson, Christopher; R. Nyholt, Dale; E. R. Ollier, William; Palotie, Aarno; Paternoster, Lavinia; L. Pedersen, Nancy; Petrovic, Katja; J. Porteous, David; Räikkönen, Katri; M. Ring, Susan; Robino, Antonietta; Rostapshova, Olga; Rudan, Igor; Rustichini, Aldo; Salomaa, Veikko; R. Sanders, Alan; Sarin, Antti‐Pekka; Schmidt, Helena; J. Scott, Rodney; H. Smith, Blair; A. Smith, Jennifer; A. Staessen, Jan; Steinhagen–Thiessen, Elisabeth; Strauch, Konstantin; Terracciano, Antonio; D. Tobin, Martin; Ulivi, Sheila; Vaccargiu, Simona; Quaye, Lydia; J.A. van Rooij, Frank; Venturini, Cristina; A. E. Vinkhuyzen, Anna; Völker, Uwe; Völzke, Henry; M. Vonk, Judith; Vozzi, Diego; Waage, Johannes; B. Ware, Erin; Willemsen, Gonneke; Attia, John; A. Bennett, David; Berger, Klaus; Bertram, Lars; Bisgaard, Hans; I. Boomsma, Dorret; B. Borecki, Ingrid; Bültmann, Ute; F. Chabris, Christopher; Cucca, Francesco; Cusi, Daniele; J. Deary, Ian; V. Dedoussis, George; M. van Duijn, Cornelia; G. Eriksson, Johan; Franke, Barbara; Franke, Lude; Gasparini, Paolo; V. Gejman, Pablo; Gieger, Christian; Grabe, Hans-Jörgen; Gratten, Jacob; J. F. Groenen, Patrick; Guðnason, Vilmundur; van der Harst, Pim; Hayward, Caroline; A. Hinds, David; Hoffmann, Wolfgang; Hyppönen, Elina; G. Iacono, William; Jacobsson, Bo; Järvelin, Marjo‐Riitta; Jöckel, Karl-Heinz; Kaprio, Jaakko; L. R. Kardia, Sharon; Lehtimäki, Terho; F. Lehrer, Steven; K. E. Magnusson, Patrik; G. Martin, Nicholas; McGue, Matt; Metspalu, Andres; Pendleton, Neil; W.J.H. Penninx, Brenda; Perola, Markus; Pirastu, Nicola; Pirastu, Mario; Polašek, Ozren; Posthuma, Danielle; Power, Christine; A. Province, Michael; J. Samani, Nilesh; Schlessinger, David; Schmidt, Reinhold; I. A. Sørensen, Thorkild; D. Spector, Tim; Stefansson, Kari; Thorsteinsdottir, Unnur; Thurik, Roy; J. Timpson, Nicholas; Tiemeier, Henning; Y. Tung, Joyce; G. Uitterlinden, André; Vitart, Véronique; Vollenweider, Péter; R. Weir, David; F. Wilson, James; F. Wright, Alan; Conley, Dalton; F. Krueger, Robert; Davey Smith, George; Hofman, Albert; I. Laibson, David; E. Medland, Sarah; N. Meyer, Michelle; Yang, Jian; Johannesson, Magnus; M. Visscher, Peter; Esko, Tõnu; Koellinger, Philipp; Cesarini, David; J. Benjamin, Daniel

doi:10.1038/nature17671

Public

Genome-wide association study identifies 74 loci associated with educational attainment

Published in Nature • May 10, 2016

Authors:

Aysu Okbay

Jonathan Beauchamp

Mark Alan Fontana

Abstract

A genome-wide association study in 293,723 individuals identifies 74 genetic variants associated with educational attainment, which, although only explaining a small proportion of the variation in educational attainment, highlights candidate genes and pathways for further study. The level of educati...

Subject

Educational attainment

Genome-wide association study

Biobank

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