Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia

Liu, Yuanfang; Wang, Baiyan; Zhang, Weina; Huang, Jin-Yan; Li, Ben-Shang; Zhang, Ming; Jiang, Lu; Li, Jianfeng; Wang, Mingjie; Dai, Yu‐Jun; Zhang, Ziguan; Wang, Qiang; Kong, Jie; Chen, Bing; Zhu, Yongmei; Weng, Xiangqin; Shen, Zhixiang; Li, Junmin; Wang, Jin; Yan, Xiaojing; Li, Yan; Liang, Yingmin; Liu, Li; Chen, Xiequn; Zhang, Wanggang; Yan, Jinsong; Hu, Jianda; Shen, Shuhong; Chen, Jing; Gu, Long-Jun; Pei, Deqing; Li, Yongjin; Wu, Gang; Zhou, Xin; Ren, Ruibao; Cheng, Cheng; Yan, Jinsong; Wang, Kankan; Wang, Shengyue; Zhang, Jinghui; Mi, Jian‐Qing; Pui, Ching‐Hon; Tang, Jingyan; Zhu, Chen; Chen, Sai‐Juan

doi:10.1016/j.ebiom.2016.04.038

Public

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia

Published in EBioMedicine • May 13, 2016

Authors:

Yuanfang Liu

Baiyan Wang

Weina Zhang

Abstract

Genomic landscapes of 92 adult and 111 pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL) were investigated using next-generation sequencing and copy number alteration analysis. Recurrent gene mutations and fusions were tested in an additional 87 adult and 93 pediatric patients. Amo...

Subject

Epigenetics

Biology

Fusion gene

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