Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function

G. Woodruff, Prescott; Graham Barr, R.; R. Bleecker, Eugene; A. Christenson, Stephanie; Couper, David; L. Curtis, Jeffrey; Gouskova, Natalia; N. Hansel, Nadia; A. Hoffman, Eric; E. Kanner, Richard; C. Kleerup, Eric; C. Lazarus, Stephen; J. Martínez, Fernando; Paine, Robert; I. Rennard, Stephen; P. Tashkin, Donald; K. Han, MeiLan

doi:10.1056/nejmoa1505971

Public

Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function

Published in New England Journal of Medicine • May 11, 2016

Authors:

Prescott G. Woodruff

R. Graham Barr

Eugene R. Bleecker

Abstract

BACKGROUND: Currently, the diagnosis of chronic obstructive pulmonary disease (COPD) requires a ratio of forced expiratory volume in 1 second (FEV1) to forced vital capacity (FVC) of less than 0.70 as assessed by spirometry after bronchodilator use. However, many smokers who do not meet this definit...

Subject

Vital capacity

Spirometry

Medicine

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