Efficacy and Safety of Sirolimus in the Treatment of Complicated Vascular Anomalies

M. Adams, Denise; C. Trenor, Cameron; M. Hammill, Adrienne; A. Vinks, Alexander; Patel, Manish; Chaudry, Gulraiz; Sue Wentzel, Mary; S. Mobberley‐Schuman, Paula; M. Campbell, Lisa; Brookbank, Christine; Gupta, Anita; Chute, Carol; Eile, Jennifer; McKenna, Jesse; C. Merrow, Arnold; Fei, Lin; Hornung, Lindsey; Seid, Michael; Roshni Dasgupta, A.; Dickie, Belinda; G. Elluru, Ravindhra; W. Lucky, Anne; Weiss, Brian; G. Azizkhan, Richard

doi:10.1542/peds.2015-3257

Public

Efficacy and Safety of Sirolimus in the Treatment of Complicated Vascular Anomalies

Published in PEDIATRICS • Jan 18, 2016

Authors:

Denise M. Adams

Cameron C. Trenor

Adrienne M. Hammill

Abstract

BACKGROUND AND OBJECTIVES: Complicated vascular anomalies have limited therapeutic options and cause significant morbidity and mortality. This Phase II trial enrolled patients with complicated vascular anomalies to determine the efficacy and safety of treatment with sirolimus for 12 courses; each co...

Subject

Medicine

Sirolimus

Intensive care medicine

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