Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

Strakova, Andrea; Ní Leathlobhair, Máire; Wang, Guodong; Yin, Tingting; Airikkala‐Otter, Ilona; L. Allen, Janice; M. Allum, Karen; Bansse-Issa, Leontine; Bisson, Jocelyn; Castillo Domracheva, Artemio; Ferreira de Castro, Karina; M. Corrigan, Anne; R. Cran, Hugh; T. Crawford, Jane; M Cutter, Stephen; Keenan, Laura; M. Donelan, Edward; A. Faramade, Ibikunle; Flores Reynoso, Erika; Fotopoulou, Eleni; N. Fruean, Skye; Gallardo-Arrieta, Fanny; Glebova, Olga; F. Häfelin Manrique, Rodrigo; Henriques, Joaquim; A. Ignatenko, Natalia; Koenig, Debbie; Lanza‐Perea, Marta; Lobetti, Remo; M. Lopez Quintana, Adriana; Losfelt, Thibault; Marino, Gabriele; Martincorena, Iñigo; Simón Martínez-Castañeda, José; Fernanda Martínez-López, Mayra; J. Meyer, Michael; Nakanwagi, Berna; Barboza De Nardi, Andrígo; Neunzig, Winifred; J. Nixon, Sally; M Onsare, Marsden; Ortega‐Pacheco, Antonio; C. Peleteiro, Maria; J. Pye, Ruth; F. Reece, John; Rojas Gutierrez, Jose; Sadia, Haleema; K. Schmeling, Sheila; Shamanova, Olga; K Ssuna, Richard; E. Steenland-Smit, Audrey; Svitich, Alla; Thoya Ngoka, Ismail; Alexandru Vițălaru, Bogdan; P. de Vos, Anna; P. de Vos, J.; Walkinton, Oliver; C. Wedge, David; Wehrle-Martinez, Alvaro; G. van der Wel, Mirjam; A. E. Widdowson, Sophie; P. Murchison, Elizabeth

doi:10.7554/elife.14552

Public

Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

Published in eLife • May 16, 2016

Authors:

Andrea Strakova

Máire Ní Leathlobhair

Guodong Wang

Abstract

Canine transmissible venereal tumour (CTVT) is a clonally transmissible cancer that originated approximately 11,000 years ago and affects dogs worldwide. Despite the clonal origin of the CTVT nuclear genome, CTVT mitochondrial genomes (mtDNAs) have been acquired by periodic capture from transient ho...

Subject

Mitochondrial DNA

Biology

Genome

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