ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

Bentebibel, Salah-Eddine; Khurana, Surender; Schmitt, Nathalie; Kurup, Parvathi; Mueller, Cynthia; Obermoser, Gerlinde; Karolina Palucka, A.; A. Albrecht, Randy; Garcia-Sastre, Adolfo; Golding, Hana; Ueno, Hideki

doi:10.1038/srep26494

Public

ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

Shared by NobleBlocks on May 27, 2016 • 12:00 AM UTC

Authors:

Salah-Eddine Bentebibel

Surender Khurana

Nathalie Schmitt

Abstract

Abstract The immune mechanism leading to the generation of protective antibody responses following influenza trivalent inactivated vaccine (TIV) vaccinations remains largely uncharacterized. We recently reported that TIV vaccination induced a transient increase of circulating ICOS + PD-1 + CXCR3 + T...

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