A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL)

Vodinelich, L.; Tax, W.J.M.; Bai, Yan; Pegram, S; J Capel, P; Greaves, MF

doi:10.1182/blood.v62.5.1108.1108

Public

A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL)

Published in Blood • Nov 1, 1983

Authors:

L. Vodinelich

W.J.M. Tax

Yan Bai

Abstract

The selectivity of a monoclonal anti-T antibody, designated WT1, has been assessed in a series of 906 leukemias and lymphomas. In acute lymphoblastic leukemias, WT1 reacts comprehensively and selectively with thymic acute lymphoblastic leukemia (ALL) cells in untreated or relapsed patients, thus ove...

Subject

Monoclonal antibody

Antigen

Biology

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