Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma

Z. Usmani, Saad; M. Weiss, Brendan; Plesner, Torben; J. Bahlis, Nizar; Belch, Andrew; Lonial, Sagar; M. Lokhorst, Henk; M. Voorhees, Peter; G. Richardson, Paul; Chari, Ajai; Kate Sasser, A.; Axel, Amy; Feng, Huaibao; Uhlar, Clarissa; Wang, Jianping; Khan, Imran; Ahmadi, Tahamtan; Nahi, Hareth

doi:10.1182/blood-2016-03-705210

Public

Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma

Published in Blood • May 24, 2016

Authors:

Saad Z. Usmani

Brendan M. Weiss

Torben Plesner

Abstract

The efficacy and favorable safety profile of daratumumab monotherapy in multiple myeloma (MM) was previously reported. Here, we present an updated pooled analysis of 148 patients treated with daratumumab 16 mg/kg. Data were combined from part 2 of a first-in-human phase 1/2 study of patients who rel...

Subject

Daratumumab

Medicine

Refractory (planetary science)

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