Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF–TIMI 48 Trial

Kato, Eri; P. Giugliano, Robert; T. Ruff, Christian; Koretsune, Yukihiro; Yamashita, Takeshi; Gábor Kiss, Róbert; Nordio, Francesco; A. Murphy, Sabina; Kimura, Tetsuya; Jin, James; Lanz, Hans; Mercuri, Michele; Braunwald, Eugene; M. Antman, Elliott

doi:10.1161/jaha.116.003432

Public

Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF–TIMI 48 Trial

Published in Journal of the American Heart Association • May 6, 2016

Authors:

Eri Kato

Robert P. Giugliano

Christian T. Ruff

Abstract

BACKGROUND: Elderly patients with atrial fibrillation are at higher risk of both ischemic and bleeding events compared to younger patients. In a prespecified analysis from the ENGAGE AF-TIMI 48 trial, we evaluate clinical outcomes with edoxaban versus warfarin according to age. METHODS AND RESULTS: ...

Subject

Edoxaban

Atrial fibrillation

TIMI

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