Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

The cross-talk between dynamic microtubules and integrin-based adhesions to the extracellular matrix plays a crucial role in cell polarity and migration. Microtubules regulate the turnover of adhesion sites, and, in turn, focal adhesions promote the cortical microtubule capture and stabilization in ... View More