Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

Strong, Randy; A. Miller, Richard; Antebi, Adam; M. Astle, Clinton; A. Bogue, Molly; S. Denzel, Martin; Fernández, Elizabeth; Flurkey, Kevin; L. Hamilton, Karyn; W. Lamming, Dudley; A. Javors, Martin; Pedro de Magalhães, João; Anthony Martinez, Paul; M. McCord, Joe; F. Miller, Benjamin; Müller, Michael; F. Nelson, James; Ndukum, Juliet; Ed Rainger, G.; Richardson, Arlan; M. Sabatini, David; B. Salmon, Adam; W. Simpkins, James; T. Steegenga, Wilma; L. Nadon, Nancy; E. Harrison, David

doi:10.1111/acel.12496

Public

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

Published in Aging Cell • Jun 16, 2016

Authors:

Randy Strong

Richard A. Miller

Adam Antebi

Abstract

The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We report the effects of lifelong treatment of mice wit...

Subject

Nordihydroguaiaretic acid

Longevity

Biology

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