Hyperthermia inhibits transforming growth factor beta-induced epithelial-mesenchymal transition (EMT) in HepG2 hepatocellular carcinoma cells.

XM, Xu; GJ, Yuan; QW, Li; SL, Shan; S, Jiang

doi:10.5754/hge12404

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Hyperthermia inhibits transforming growth factor beta-induced epithelial-mesenchymal transition (EMT) in HepG2 hepatocellular carcinoma cells.

Shared by NobleBlocks on Oct 1, 2012 • 12:00 AM UTC

Authors:

Xu XM

Yuan GJ

Li QW

Abstract

Background/aims EMT plays an essential role in tumor progression and metastasis. Hyperthermia is a potent approach for cancers with low side effects. However, the effect of hyperthermia on EMT of cancer cells is unknown.Methodology Cells were treated with TGF-β1 and epidermal growth factor for 96 h ...

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