Pro‐osteoclastic <i>in vitro</i> effect of Polyethylene‐like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening

Brulefert, Kévin; A. Córdova, Luis; Brulin, Bénédicte; Faucon, Adrien; Hulin, Philippe; Nédellec, Steven; Gouin, F.; Passuti, Norbert; Ishow, Éléna; Heymann, Dominique

doi:10.1002/jbm.a.35803

Public

Pro‐osteoclastic in vitro effect of Polyethylene‐like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening

Published in Journal of Biomedical Materials Research Part A • Jun 2, 2016

Authors:

Kévin Brulefert

Luis A. Córdova

Bénédicte Brulin

Abstract

Polyethylene micro-sized wear particles released from orthopedic implants promote inflammation and osteolysis; however, less is known about the bioactivity of polyethylene nanosized wear particles released from the last generation of polymer-bearing surfaces. We aim to assess the internalization of ...

Subject

Osteolysis

Osteoclast

Materials science

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