Alternative Macrophage Activation Is Increased in Asthma

Girodet, Pierre‐Olivier; Nguyen, Daniel; D. Mancini, John; Hundal, Mandeep; Zhou, Xiaobo; Israel, Elliot; Cernadas, Manuela

doi:10.1165/rcmb.2015-0295oc

Public

Alternative Macrophage Activation Is Increased in Asthma

Published in American Journal of Respiratory Cell and Molecular Biology • Jun 1, 2016

Authors:

Pierre‐Olivier Girodet

Daniel Nguyen

John D. Mancini

Abstract

Abstract The immune responses of type 2 T helper cells (Th2) play an important role in asthma and promote the differentiation of alternatively activated (M2) macrophages. M2 macrophages have been increasingly understood to contribute to Th2 immunity. We hypothesized that M2 macrophages are altered i...

Subject

Immunology

Macrophage

Monocyte

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