Indoleamine metabolites in the cerebrospinal fluid of depressed patients before and during treatment with nortriptyline

Åsberg, Marie; Bertilsson, Leif; Tuck, D.; Cronholm, Börje; Sjöqvist, Folke

doi:10.1002/cpt1973142277

Public

Indoleamine metabolites in the cerebrospinal fluid of depressed patients before and during treatment with nortriptyline

Published in Clinical Pharmacology & Therapeutics • Mar 1, 1973

Authors:

Marie Åsberg

Leif Bertilsson

D. Tuck

Abstract

Cerebrospinal fluid (CSF) levels of the indoleamine metabolites, 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) and indole‐3‐acetic acid (IAA) were measured by a specific mass fragmentographic method in 43 depressed psychiatric in‐patients. The mean level of 5‐HIAA was 19.7 ± 7.9 ng per milliliter. The 5‐HI...

Subject

Nortriptyline

Liter

Cerebrospinal fluid

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