Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

H. Goodson, William; Lowe, Leroy; O. Carpenter, David; Gilbertson, Michael; Manaf Ali, Abdul; Lopez de Cerain Salsamendi, Adela; Lasfar, Ahmed; Carnero, Amancio; Azqueta, Amaya; Amedei, Amedeo; K. Charles, Amelia; Collins, Andrew; Ward, Andrew; C. Salzberg, Anna; Colacci, Annamaria; Olsen, Ann‐Karin; Berg, Arthur; J. Barclay, Barry; P. Zhou, Binhua; Blanco‐Aparicio, Carmen; J. Baglole, Carolyn; Dong, Chenfang; Mondello, Chiara; Hsu, Chia-Wen; C. Naus, Christian; G. Yedjou, Clément; S. Curran, Colleen; W. Laird, Dale; C. Koch, Daniel; J. Carlin, Danielle; W. Felsher, Dean; Roy, Debasish; G. Brown, Dustin; A. Ratovitski, Edward; P. Ryan, Elizabeth; Corsini, Emanuela; Rojas, Emilio; Moon, Eun‐Yi; Laconi, Ezio; Marongiu, Fabio; Al‐Mulla, Fahd; Chiaradonna, Ferdinando; Darroudi, F.; Martin, Francis; van Schooten, Frederik‐Jan; S. Goldberg, Gary; Wagemaker, Gerard; N. Nangami, Gladys; M. Calaf, Gloria; P. Williams, Graeme; T. Wolf, Gregory; Koppen, Gudrun; Brunborg, Gunnar; Kim Lyerly, H.; Krishnan, Harini; Ab Hamid, Hasiah; Yasaei, Hemad; Sone, Hideko; Kondoh, Hiroshi; Salem, Hosni; Hsu, Hsue‐Yin; Ho Park, Hyun; Koturbash, Igor; R. Miousse, Isabelle; Ivana Scovassi, A.; E. Klaunig, James; Vondráček, Jan; Raju, Jayadev; Roman, Jesse; Pierce Wise, John; R. Whitfield, Jonathan; Woodrick, Jordan; Christopher, Joseph; Ochieng, Josiah; Fernando Martínez-Leal, Juan; Weisz, Judith; Kravchenko, Julia; Sun, Jun; R. Prudhomme, Kalan; Badri Narayanan, Kannan; Cohen-Solal, Karine; Moorwood, Kim; Gonzalez, Laetitia; Soucek, Laura; Jian, Le; S. D’Abronzo, Leandro; Lin, Liang; Li, Lin; Gulliver, Linda; J. McCawley, Lisa; Memeo, Lorenzo; Vermeulen, Louis; Leyns, Luc; Zhang, Luoping; Valverde, Mahara; Khatami, Mahin; Fiammetta Romano, Maria; Chapellier, Marion; A. Williams, Marc; Wade, Mark; H. Manjili, Masoud; E. Lleonart, Matilde; Xia, Menghang; J. Guzman, Michael; V. Karamouzis, Michalis; Kirsch‐Volders, Micheline; Vaccari, Monica; B. Kuemmerle, Nancy; Singh, Neetu; Cruickshanks, Nichola; Kleinstreuer, Nicole; Van Larebeke, Nicolas; Ahmed, Nuzhat; Ogunkua, Olugbemiga; K Krishnakumar, P; Vadgama, Pankaj; A. Marignani, Paola; Ghosh, P.; Ostrosky‐Wegman, Patricia; A. Thompson, Patricia; Dent, Paul; Heneberg, Petr; D. Darbre, Philippa; Sing Leung, Po; Nangia‐Makker, Pratima; Cheng, Qiang; Brooks Robey, R.; Al‐Temaimi, Rabeah; Roy, Rabindra; Andrade-Vieira, Rafaela; Kumar Sinha, Ranjeet; Mehta, Rekha; Vento, Renza; Di Fiore, Riccardo; Ponce‐Cusi, Richard; Dornetshuber-Fleiss, Rita; Nahta, Rita; C. Castellino, Robert; Palorini, Roberta; Abd Hamid, Roslida; A. S. Langie, Sabine; E. Eltom, Sakina; A. Brooks, Samira; Ryeom, Sandra; S. Wise, Sandra; Bay, Sarah; A. Harris, Shelley; Papagerakis, Silvana; Romano, Simona; Pavanello, Sofia; Eriksson, Staffan; Forte, Stefano; C. Casey, Stephanie; Luanpitpong, Sudjit; Jin Lee, Tae; Otsuki, Takemi; Chen, Tao; Massfelder, Thierry; Thomas Sanderson, J.; Guarnieri, Tiziana; Hultman, Tove; Dormoy, Valérian; Odero‐Marah, Valerie; Sabbisetti, Venkata; Maguer‐Satta, Véronique; Kimryn Rathmell, W.; Engström, Wilhelm; K. Decker, William; H. Bisson, William; Rojanasakul, Yon; A. Luqmani, Yunus; Chen, Zhenbang; Hu, Zhiwei

doi:10.1093/carcin/bgv039

Public

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Published in Carcinogenesis • Jun 1, 2015

Authors:

William H. Goodson

Leroy Lowe

David O. Carpenter

Abstract

Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is betwe...

Subject

Carcinogen

Environmental chemistry

Chemistry

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